Career Profile

I obtained a Computer Science degree in 2011 and a PhD in 2016 working in the field of Artificial Intelligence applied to the analysis of mass spectrometry data at Universidade de Vigo, under Dr. Daniel Glez-Peña and Dr. Miguel Reboiro-Jato supervision. The combination of Artificial Intelligence with Life sciences (especially Bioinformatics) defines my main research line since then. I have being member of the SING research group (Next Generation Computer Systems Group) since 2012, where I worked as Pre and Postdoctoral Researcher for many years (2012-2022). I collaborate with the Phenotypic Evolution research group at Instituto de Investigação e Inovação (Porto, Portugal), where I worked as Junior Researcher between May and December 2021. I am also specialized in the development of scientific software applications (mainly in Java) and data analysis (R, Python), with special interest on the creation of automated analysis pipelines. In October 2022, I got a position as Assistant Professor at the Informatics Department of Universidade de Vigo, where I currently develop my teaching and research activities.

Experiences

Assistant Professor

2022 - Present
Universidade de Vigo (Ourense, Spain)

Postdoctoral Researcher "María Zambrano"

2022
Universidade de Vigo (Ourense, Spain)

Junior Researcher

2021
i3S - Instituto de Investigação e Inovação da Universidade do Porto (Porto, Portugal)

Postdoctoral Researcher

2018 - 2021
Universidade de Vigo (Ourense, Spain)

Postdoctoral Researcher

2017 - 2018
Instituto de Biologia Molecular e Celular / i3S - Instituto de Investigação e Inovação da Universidade do Porto (Porto, Portugal)

Postdoctoral Researcher

2016 - 2017
Faculdade de Ciências e Tecnologia / Universidade Nova de Lisboa (Caparica, Portugal)

Predoctoral Researcher

2012 - 2016
Universidade de Vigo (Ourense, Spain)

Researcher

2011 - 2012
Universidade de Vigo (Ourense, Spain)

Training Courses

⬇ AI for Medicine Specialization ⬇

AI for Medical Prognosis (2020). deeplearning.ai through Coursera.
AI for Medical Diagnosis (2020). deeplearning.ai through Coursera.

⬇ Deep Learning Specialization ⬇

Sequence Models (2020). deeplearning.ai through Coursera.
Convolutional Neural Networks (2020). deeplearning.ai through Coursera.
Structuring Machine Learning Projects (2020). deeplearning.ai through Coursera.
Improving Deep Neural Networks: Hyperparameter tuning, Regularization and Optimization (2020). deeplearning.ai through Coursera.
Neural Networks and Deep Learning (2019). deeplearning.ai through Coursera.
Understanding Clinical Research: Behind the Statistics (2016). University of Cape Town through Coursera.
Getting and Cleaning Data (2015). Johns Hopkins University through Coursera.
Exploratory Data Analysis (2015). Johns Hopkins University through Coursera.
Machine Learning (2014). Stanford University through Coursera.
Computing for Data Analysis (2012). Johns Hopkins University through Coursera.

Media

Julia Sánchez, de Gales a Galicia con un plan para captar talento científico: "Fue un suicidio profesional"

17/04/2024 - Faro de Vigo

Ourense participa en la red estatal para la detección de cáncer de colon mediante IA

16/04/2024 - Faro de Vigo

Estudan previr o cancro colorrectal usando a IA en Ourense

16/04/2024 - La Región

Investigadores gallegos integran una red nacional que busca mejorar el diagnóstico de cáncer de colon con inteligencia artificial

16/04/2024 - La Voz de Galicia

Un proxecto da UVigo sérvese da IA para mellorar a detección de cancro colorrectal

17/04/2024 - GCiencia

A rede estatal AI4PolypNet traballará na mellora dos sistemas de detección e de diagnose de cancro colorrectal empregando intelixencia artificial

16/04/2024 - DUVI

Presentado con sobresaliente 'MyBrain-Seq': un software para estudiar las enfermedades neuropsiquiátricas

16/11/2023 - IDIS

Todo sobre myBrain-Seq

07/2023 - Código Cero

La UVigo lanza un programa para tratar mejor el cáncer

20/06/2023 - Atlántico Diario

Un equipo da UVigo busca fármacos contra o cancro persoalizados e máis eficaces

20/06/2023 - GCiencia

O programa PanDrugs2 busca os fármacos máis eficaces para o cancro de cada paciente

19/06/2023 - Diario da Universidade de Vigo (DUVI)

MyBrain-Seq: el software para encontrar biomarcadores de microARN en enfermedades neuropsiquiátricas

14/06/2023 - ConSalud.es

MyBrain-Seq, un software libre para estudar as enfermidades neuropsiquiátricas

06/05/2023 - Televisión de Galicia (TVG)

Identifican trastornos mentales a través del ARN

28/04/2023 - Atlántico Diario

Un programa gallego ayuda a diagnosticar mejor enfermedades y trastornos mentales

27/04/2023 - Faro de Vigo

La UVigo idea en Ourense un programa para investigar la depresión

27/04/2023 - La Región

Un software 'gallego' permite encontrar biomarcadores genéticos en enfermedades mentales

26/04/2023 - El Correo Gallego

Un equipo galego deseña un software para estudar enfermidades neuropsiquiátricas

26/03/2023 - GCiencia

Investigadores da UVigo e do IDIS desenvolven un software para estudar as enfermidades neuropsiquiátricas

26/03/2023 - DUVI

Investigadores alertan: "La LOSU puede aumentar la 'endogamia'"

15/03/2023 - Atlántico Diario

Desenvolvido método de monitorização do cancro da bexiga a partir de análise à urina

23/02/2023 - Público

Cancro da bexiga: mais cómodo e preciso, há um novo método de monitorização

23/02/2023 - SIC Notícias

Los jóvenes investigadores gallegos en la diáspora reclaman oportunidades para regresar

28/12/2022 - Faro de Vigo

Hugo López, doutor especialista en IA: "A Axencia de Intelixencia Artificial pon Galiza no mapa

27/12/2022 - Nòs Diario

Preto de 80 mozas e mozos investigadores que traballan no estranxeiro participaron no IYI Meeting, celebrado por vez primeira en Vigo

27/12/2022 - DUVI

Vigo acollerá por primeira vez a XIII Reunión de Jóvenes Investigador@s en el Extranjero

16/12/2022 - DUVI

Galardonan al grupo de investigación SING en Vigo

16/11/2022 - La Región

El campus afianza lazos interuniversitarios con casi 300 estancias de investigación en ocho años

14/03/2022 - Faro de Vigo

Participación no programa Vigo a debate: A investigación científica

21/04/2021 - TV / TeleVigo

Voces contra la precariedad en ciencia

16/04/2021 - Faro de Vigo

Entrevista en el programa La Brújula de Galicia (a partir del 7'10").

15/04/2021 - Onda Cero

Investigadores gallegos se movilizan contra la reforma de la ley de Ciencia

15/04/2021 - La Voz de Galicia

Entrevista en el programa A Vivir Galicia: Investigadores contra a Lei de Ciencia de Pedro Duque.

10/04/2021 - Cadena SER Galicia

Entrevista en el noticiario local de A Coruña en Radio 5 (a partir del 9'30")

08/10/2020 - Radio 5

Entrevista en el programa A Vivir Galicia (a partir del 22'30")

20/03/2020 - Cadena SER Galicia

Projects (Software development)

Auto-Phylo (2023 - Present): pipeline maker software for phylogenetic studies.
PanDrugs2 (2022 - 2023): a bioinformatics platform to prioritize anticancer drug treatments according to individual multi-omics data.
Phlogenetic Tree Collapser (2021 - Present): a tool to collapse phylogenetic trees using taxonomic information.
DREIMT (2018 - 2020): a tool for immune modulation drug prioritization.
compi (2018 - Present): an application framework for portable computational pipelines.
Bioinformatics Docker Images Project (2018 - Present): a repository of curated, well-documented Docker images for bioinformatics software and pipelines.
EvoPPI (2017 - Present): an open source web application for easily comparing publicly available data from the main Protein-Protein Interaction (PPI) databases for distinct species.
SEDA (2017 - Present): an open source application for processing FASTA files containing DNA and protein sequences.
DEWE (2016 - 2019): an open source application for performing differential expression analysis in RNA-Seq data.
S2P (2016 - 2018): an open source application for fast and easy processing of 2D-gel and MALDI-based mass spectrometry protein data.
LA-iMageS (2015 - 2016): an open source application to generate 2D/3D images for the elements present in a set of LA-ICP-MS (Laser Ablation Inductively Coupled Plasma Mass Spectrometry) spectra.
GC4S (2014 - Present): a Java library of GUI components for Swing.
RUbioSeq+ (2014 - 2016): a software suite to perform NGS data analysis in a automatic, paralellized and reliable way which is crucial to eliminate manual steps and to speed up result generation.
Mass-Up (2013 - 2020): an open-source mass spectrometry software for proteomics designed to support the preprocessing and analysis of MALDI-TOF mass spectrometry data.
BioAnnote (2011 - 2012): an annotator Desktop application able to annotate biomedical texts by using different high-quality online resources, such as Medlineplus and Freebase.
PileLine GUI (2010 - 2011): a Java Swing front-end for the PileLine toolkit along with a genome browser.

Compi pipelines

myBrain-Seq (2022 - Present): miRNA-Seq analysis of neuropsychiatric data.
Conserved Genome Annotation (CGA) Pipeline (2021 - Present): CDS annotation by automating the steps that researchers usually follow when performing manual annotations.
Auto-PSS-Genome (Automatic Positively Selected Sites Genome) (2020): Automatic detection of positively selected sites in complete genomes.
IPSSA (Integrated Positively Selected Sites Analyses) (2020): Automatic detection of positively selected amino acid sites.
GenomeFastScreen (2020): Fast identification of genes with positively selected amino acid sites for detailed analyses in complete genomes.
FastScreen (2019 - 2020): Fast identification of genes with positively selected amino acid sites for detailed analyses.

Side projects

This section collects side projects developed by my own on my free time, mostly for fun and for practising programming while doing something useful.
sklearn-leave-one-out-cv (2023): Functions and examples to perform Leave-One-Out Cross-Validation with scikit-learn.
Garmin Data Analysis (2023): Python scripts to process Garmin data.
Alertas de Carreiras en Galicia (2022 - 2023): Python scripts to automatically collect information about running events in Galicia.
Genetic Codes (2020): Ready-to-use files of the genetic codes downloaded from the National Center for Biotechnology Information (NCBI).
MemoryManagement (2015): A Java implementation that simulates different memory allocation strategies (first, next, best and worst) for multiprogramming systems.

Publications

P. Davila-Piñón; A. Nogueira-Rodríguez; A.I. Díez-Martín; L. Codesido; J. Herrero; M. Puga; L. Rivas; E. Sánchez; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato; H. López-Fernández; J. Cubiella (2024) Optical diagnosis in still images of colorectal polyps: comparison between expert endoscopists and PolyDeep, a Computer-Aided Diagnosis system. Frontiers in Oncology. Accepted manuscript. ISSN: 2234-943X
P. Ferreira; R. Soares; H. López-Fernández; N. Vázquez; M. Reboiro-Jato; C. P. Vieira; J. Vieira (2024) Multiple Lines of Evidence Support 199 SARS-CoV-2 Positively Selected Amino Acid Sites. International Journal of Molecular Sciences. Volume 25(4), Article Number 2428. ISSN: 1422-0067
H. López-Fernández; M. Pinto; C. P. Vieira; P. Duque; M. Reboiro-Jato; J. Vieira (2024) auto-phylo v2 and auto-phylo-pipeliner: building advanced, flexible, and reusable pipelines for phylogenetic inferences, estimation of variability levels and identification of positively selected amino acid sites. Journal of Integrative Bioinformatics. Available online. ISSN: 1613-4516
L. B. Carvalho; S. Jorge; H. López-Fernández; C. Lodeiro; R. Dhir; L. Campos Pinheiro; M. Medeiros; H. M. Santos; J. L. Capelo (2023) Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation. Clinical Proteomics. Volume 20, 54. ISSN: 1559-0275
M.J. Jiménez-Santos; A. Nogueira-Rodríguez; E. Piñeiro-Yáñez; H. López-Fernández; S. García-Martín; P. Gómez-Plana; M. Reboiro-Jato; G. Gómez-López; D. Glez-Peña; F. Al-Shahrour (2023) PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data. Nucleic Acids Research. Volume 51 (Web Server Issue W1), pp. W411-W418. ISSN: 0305-1048
D. Pérez-Rodríguez; R.C. Agís-Balboa; H. López-Fernández (2023) MyBrain-Seq: A Pipeline for MiRNA-Seq Data Analysis in Neuropsychiatric Disorders. Biomedicines. Volume 11 (4), 1230. ISSN: 2227-9059
A. Nogueira-Rodríguez; D. Glez-Peña; M. Reboiro-Jato; H. López-Fernández (2023) Negative Samples for Improving Object Detection—A Case Study in AI-Assisted Colonoscopy for Polyp Detection. Diagnostics. Volume 13(5), 966. ISSN: 2075-4418
D. Pérez-Rodríguez; M. Arancha Penedo; T. Rivera-Baltanás; T. Peña-Centeno; S. Burkhardt; A. Fischer; J. M. Prieto-González; J. M. Olivares Díez; H. López-Fernández; R. C. Agís-Balboa (2023) MiRNA differences related to treatment resistant schizophrenia. International Journal of Molecular Sciences. Volume 24(3), 1891. ISSN: 1422-0067
L. B. Carvalho; J. L. Capelo; C. Lodeiro; R. Dhirc; L. Campos Pinheiro; H. López-Fernández; G. Martins; M. Medeiros; H. M. Santos (2023) Pathway-guided monitoring of the disease course in bladder cancer with longitudinal urine proteomics. Communications Medicine. Volume 3, Article Number 8. ISSN: 2730-664X
A.D. Sousa; S. Rocha; J. Vieira; M. Reboiro-Jato; H. López-Fernández; C.P. Vieira (2023) On the identification of potential novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease using EvoPPI 3. Journal of Integrative Bioinformatics. Volume 20 (2), Article Number 20220056. ISSN: 1613-4516
A. Nogueira-Rodríguez; M. Reboiro-Jato; D. Glez-Peña; H. López-Fernández (2022) Performance of Convolutional Neural Networks for Polyp Localization on Public Colonoscopy Image Datasets. Diagnostics. Volume 12(4), 898. ISSN: 2075-4418
A. Nogueira-Rodríguez; R. Domínguez-Carbajales; F. Campos-Tato; J. Herrero; M. Puga; D. Remedios; L. Rivas; E. Sánchez; Á. Iglesias; J. Cubiella; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña (2022) Real-time polyp detection model using convolutional neural networks. Neural Computing and Applications. Volume 34, pp. 10375-10396. ISSN: (Online) 1433-3058 - (Print) 0941-0643
H. López-Fernández; P. Duque; N. Vázquez; F. Fdez-Riverola; M. Reboiro-Jato; C. P. Vieira; J. Vieira (2022) SEDA: a Desktop Tool Suite for FASTA Files Processing. IEEE/ACM Transactions on Computational Biology and Bioinformatics. Volume 19(3), pp. 1850-1860. ISSN: 1545-5963
D. Pérez-Rodríguez; H. López-Fernández; R.C. Agís-Balboa (2021) Application of miRNA-seq in neuropsychiatry: a methodological perspective. Computers in Biology and Medicine. Volume 135, Article ID 104603. ISSN: 0010-4825
H. López-Fernández; O. Graña-Castro; A. Nogueira-Rodríguez; M. Reboiro-Jato; D. Glez-Peña (2021) Compi: a Framework for Portable and Reproducible Pipelines. PeerJ Computer Science. Volume 7: e593. ISSN: 2376-5992
S. Vimal; D. Pelusi; J.H. Park; F. Fdez-Riverola; M. Rocha; H. López-Fernández, guest editors (2021) Special Issue: Enabling Technologies for Genomic and sequence analysis Using Artificial Intelligence in Smart medical applications. Interdisciplinary Sciences: Computational Life Sciences. Volume 13/2. ISSN: (Online) 1867-1462 - (Print) 1913-2751
H. López-Fernández; C. P. Vieira; P. Ferreira; P. Gouveia; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira (2021) On the identification of clinically relevant bacterial amino acid changes at the whole genome level using Auto-PSS-Genome. Interdisciplinary Sciences: Computational Life Sciences. Volume 13/2, pp. 334–343. ISSN: (Online) 1867-1462 - (Print) 1913-2751
A. Nogueira-Rodríguez; R. Domínguez-Carbajales; H. López-Fernández; Á. Iglesias; J. Cubiella; F. Fdez-Riverola; M. Reboiro-Jato; D. Glez-Peña (2021) Deep Neural Networks approaches for detecting and classifying colorectal polyps. Neurocomputing. Volume 423, pp. 721-734. ISSN: 0925-2312
K. Troulé; H. López-Fernández; S. García-Martín; M. Reboiro-Jato; C. Carretero-Puche; J. Martorell-Marugán; G. Martín-Serrano; P. Carmona-Sáez; D. González-Peña; F. Al-Shahrour; G. Gómez-López (2021) DREIMT: a drug repositioning database and prioritization tool for immunomodulation. Bioinformatics. Volume 37, Issue 4, pp. 578-579. ISSN: (Online) 1460-2059 - (Print) 1367-480
O. Estévez; L. Anibarro; E. Garet; Á. Pallares; L. Barcia; L. Calviño; C. Maueia; T. Mussá; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato; H. López-Fernández; N. Fonseca; R. Reljic; Á. González-Fernández (2020) An RNA-seq based machine learning approach identifies latent tuberculosis patients with an active tuberculosis profile. Frontiers in Immunology. Volume 11, article ID 1470. ISSN: 1664-3224
O. Graña-Castro; H. López-Fernández; A. Nogueira-Rodríguez; F. Fdez-Riverola; F. Al-Shahrour; D. Glez-Peña (2020) Metatax: Metataxonomics with a Compi-based pipeline for Precision Medicine. Interdisciplinary Sciences: Computational Life Sciences. Volume 12/1, pp. 252–257. ISSN: (Online) 1867-1462 - (Print) 1913-2751
S. Jorge; K. Pereira; H. López-Fernández; W. LaFramboise; R. Dhir; J. Fernández-Lodeiro; C. Lodeiro; H. M. Santos; J. L. Capelo-Martínez (2020) Ultrasonic-assisted extraction and digestion of proteins from solid biopsies followed by peptide sequential extraction hyphenated to MALDI-based profiling holds the promise of distinguishing renal oncocytoma from chromophobe renal cell carcinoma. Talanta. Volume 206, Article 120180. ISSN: 0039-9140
S. Rocha; J. Vieira; N. Vázquez; H. López-Fernández; F. Fdez-Riverola; M. Reboiro-Jato; A. D. Sousa; C. P. Vieira (2019) ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms. BMC Medical Genomics. Volume 12: 145. ISSN: 1755-8794
J. Vieira; S. Rocha; N. Vázquez; H. López-Fernández; F. Fdez-Riverola; M. Reboiro-Jato; C.P. Vieira (2019) Predicting specificities under the non-self gametophytic self-incompatibility recognition model. Frontiers in Plant Science. Volume 10, Article 879. ISSN: 1664-462X
S. Henriques; P. Duque; H. López-Fernández; N. Vázquez; F. Fdez-Riverola; M. Reboiro-Jato; C.P. Vieira; J. Vieira (2019) Multiple independent L-gulonolactone oxidase (GULO) gene losses and Vitamin C synthesis reacquisition events in non-Deuterostomian animal species. BMC Evolutionary Biology. Volume 19: 126. ISSN: 1471-2148
H. López-Fernández; A. Blanco-Míguez; F. Fdez-Riverola; B. Sánchez; A. Lourenço (2019) DEWE: a novel tool for executing differential expression RNA-Seq workflows in biomedical research. Computers in Biology and Medicine. Volume 107, pp. 197-205. ISSN: 0010-4825
N. Vázquez; H. López-Fernández; C.P. Vieira; F. Fdez-Riverola; J. Vieira; M. Reboiro-Jato (2019) BDBM 1.0: A Desktop Application for Efficient Retrieval and Processing of High Quality Sequence Data and Application to the Identification of the Putative Coffea S-locus. Interdisciplinary Sciences: Computational Life Sciences. Volume 11(1), pp. 57-67. ISSN: 1913-2751
N. Vázquez; S. Rocha; H. López-Fernández; A. Torres; R. Camacho; F. Fdez-Riverola; J. Vieira; C.P. Vieira; M. Reboiro-Jato (2019) EvoPPI 1.0: a Web Platform for Within and Between Species Multiple Interactome Comparisons and Application to Nine polyQ Proteins Determining Neurodegenerative Diseases. Interdisciplinary Sciences: Computational Life Sciences. Volume 11(1), pp. 45-56. ISSN: 1913-2751
H. López-Fernández; P. Duque; S. Henriques; N. Vázquez; F. Fdez-Riverola; C.P. Vieira; M. Reboiro-Jato; J. Vieira (2019) Bioinformatics Protocols for Quickly Obtaining Large-Scale Data Sets for Phylogenetic Inferences. Interdisciplinary Sciences: Computational Life Sciences. Volume 11(1), pp. 1-9. ISSN: 1913-2751
H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; R. Laza; R. Pavón; F. Fdez-Riverola (2018) GC4S: a bioinformatics-oriented Java software library of reusable graphical user interface components. PLOS ONE. Volume 13(9): e0204474. ISSN: 1932-6203
N. Vázquez; C. P. Vieira; B. S. R. Amorim; A. Torres; H. López-Fernández; F. Fdez-Riverola; J. L. R. Sousa; M. Reboiro-Jato; J. Vieira (2018) Large scale analyses and visualization of adaptive amino acid changes projects. Interdisciplinary Sciences: Computational Life Sciences. Volume 10, pp. 24-32. ISSN: (Online) 1867-1462 - (Print) 1913-2751
O. Graña; H. López-Fernández; F. Fdez-Riverola; D. Pisano; D. Glez-Peña (2018) bicycle: a bioinformatics pipeline to analyze bisulfite sequencing data. Bioinformatics. Volume 34, Issue 8, pp. 1414-1415. ISSN: (Online) 1460-2059 - (Print) 1367-4803
J. Prates; G. Martins; H. López-Fernández; C. Lodeiro; J. L. Capelo; H. M. Santos (2018) Modulating the protein content of complex proteomes using acetonitrile. Talanta. Volume 182, pp. 333-339. ISSN: 0039-9140
F. Aparicio; M.L. Morales-Botello; M. Rubio; A. Hernando; R. Muñoz; H. López-Fernández; D. Glez-Peña; F. Fdez-Riverola; M. de la Villa; M. Maña; D. Gachet; M. de Buenaga (2018) Perceptions of the use of intelligent information access systems in university level active learning activities among teachers of biomedical subjects. International Journal of Medical Informatics. Volume 112, pp. 21-33. ISSN: 1386-5056
J.E. Araújo; H. López-Fernández; P.M. Baltazar; L. Campos-Pinheiro; F. Calais-Da-Silva; M. Carrascal; P. Videira; H.M. Santos; J.L. Capelo-Martínez (2018) Dithiothreitol-based protein equalization technology to unravel biomarkers for bladder cancer. Talanta. Volume 180, pp. 36-46. ISSN: 0039-9140
H. López-Fernández; J.E. Araújo; S. Jorge; D. Glez-Peña; M. Reboiro-Jato; F. Fdez-Riverola; H.M. Santos; J.L. Capelo-Martínez (2018) S2P: A Software Tool to Quickly Carry Out Reproducible Biomedical Research Projects Involving 2D-Gel and MALDI-TOF MS Protein Data. Computer Methods and Programs in Biomedicine. Volume 155, pp. 1-9. ISSN: 0169-2607
J. Romário de Jesus; H.M. Santos; H. López-Fernández; C. Lodeiro; M.A.Z. Arruda; J.L. Capelo-Martínez (2018) Ultrasonic-Based Membrane Aided Sample Preparation of Urine Proteomes. Talanta. Volume 178, pp. 864-869. ISSN: 0039-9140
M. Rubio-Camarillo; H. López-Fernández; G. Gómez-López; Á. Carro; J.M. Fernández; C. Fustero-Torre; F. Fdez-Riverola; D. Glez-Peña (2017) RUbioSeq+: a multiplatform application that executes parallelized pipelines to analyse next-generation sequencing data. Computer Methods and Programs in Biomedicine. Volume 138, pp. 73-81. ISSN: 0169-2607
H. López-Fernández; G. de S. Pessôa; M.A.Z. Arruda; J.L. Capelo-Martínez; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato (2016) LA-iMageS: a software for elemental distribution bioimaging using LA-ICP-MS data. Journal of Cheminformatics. Volume 8:65. ISSN: 1758-2946
H. López-Fernández; M. Reboiro-Jato; J.A. Pérez-Rodríguez; F. Fdez-Riverola; D. Glez-Peña (2016) The Artificial Intelligence Workbench: a retrospective review. Advances in Distributed Computing and Artificial Intelligence Journal. Volume 5/1, pp. 73-85. ISSN: 2255-2863
H. López-Fernández; M. Reboiro-Jato; J.A. Pérez Rodríguez; F. Fdez-Riverola; D. Glez-Peña (2016) Implementing effective machine learning-based workflows for the analysis of mass spectrometry data. Journal of Integrated OMICS, a methodological journal. Volume 6/1, pp. 1-5.ISSN: 2182-0287
H. López-Fernández (2016) Application of data mining and artificial intelligence techniques to mass spectrometry data for knowledge discovery. Revista Iberoamericana de Inteligencia Artificial. Volume 19(57), pp. 22-25. ISSN: 1988-3064
G. de S. Pessôa; J.L. Capelo-Martínez; F. Fdez-Riverola; H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; M.A.Z. Arruda (2016) Laser ablation and inductively coupled plasma mass spectrometry focusing on bioimaging from elemental distribution using MatLab software: a practical guide. Journal of Analytical Atomic Spectrometry. Volume 31, Issue 4, pp. 832-840. ISSN: 0267-9477
H. López-Fernández; H.M. Santos; J.L. Capelo; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato (2015) Mass-Up: an all-in-one open software application for MALDI-TOF mass spectrometry knowledge discovery. BMC Bioinformatics. 16:318. ISSN: 1471-2105
D. Glez-Peña; A. Lourenço; H. López-Fernández; M. Reboiro-Jato; F. Fdez-Riverola (2014) Web scraping technologies in an API world. Briefings in Bioinformatics. Volume 15, Issue 5, pp. 788-797. ISSN: (Online) 1477-4054 - (Print) 1467-5463
H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; F. Fdez-Riverola (2014) A comprehensive analysis about the influence of low-level preprocessing techniques on mass spectrometry data for sample classification. International Journal of Data Mining and Bioinformatics. Volume 10/4, pp. 455-473. ISSN: (Online) 1748-5681 - (Print) 1748-5673
M. Galesio; H. López-Fdez; M. Reboiro-Jato; S. Gómez-Meire; D. Glez-Peña; F. Fdez-Riverola; C. Lodeiro; M. Diniz; J.L. Capelo (2013) Speeding up the screening of steroids in urine: development of a user-friendly library. Steroids. Volume 78/12-13, pp. 1226-1232. ISSN: 0039-128X
H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; F. Aparicio; D. Gachet; M. Buenaga; F. Fdez-Riverola (2013) BioAnnote: A software platform for annotating biomedical documents with application in medical learning environments. Computer Methods and Programs in Biomedicine. 111/1, pp. 139-147. ISSN: 0169-2607
M. Reboiro-Jato; R. Laza; H. López-Fernández; D. Glez-Peña; F. Díaz; F. Fdez-Riverola (2013) genEnsemble: a new model for the combination of classifiers and integration of biological knowledge applied to genomic data. Expert Systems With Applications. Volume 40/1, pp. 52-63. ISSN: 0957-4174
R. López-Cortés; E. Oliveira; C. Núñez; C. Lodeiro; M. Páez de la Cadena; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; J.L. Capelo; H.M. Santos (2012) Fast human serum profiling through chemical depletion coupled to gold-nanoparticle-assisted protein separation. Talanta. Volume 100, pp. 239-245. ISSN: 0039-9140
F. Fdez-Riverola; D. Glez-Peña; H. López-Fernández; M. Reboiro-Jato; J.R. Méndez (2012) A Java application framework for scientific software development. Software: Practice & Experience. Volume 42/8, pp. 1015-1036. ISSN: 0038-0644
H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; J.R. Méndez-Reboredo; H.M. Santos; R.J. Carreira; J.L. Capelo; F. Fdez-Riverola (2011) Rapid development of proteomic applications with the AIBench framework. Journal of Integrative Bioinformatics. 8/3:171. ISSN: 1613-4516
H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; G. Gómez-López; D.G. Pisano; F. Fdez-Riverola (2011) PileLineGUI: a desktop environment for handling genome position files in next-generation sequencing studies. Nucleic Acids Research. Volume 39 (suppl 2), pp. W562-W566. ISSN: 0305-1048

Conferences

P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; S. Zarraquiños; L. de Castro; M. Herrero; N. Fernández; P. Vega; D. Remedios; A. Martínez; M. Puga; S. Alonso; N. Pin; N. García-Morales; L. Rivas; A. Ledo: R. Macenlle; L. Cid; A. Rodríguez; S. Soto; F. Baiocchi; I. Miosotis; E. Sánchez; R. Domínguez-Carbajales; A. Nogueira-Rodríguez; H. López-Fernández; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2024) Validación clínica de Polydeep, un sistema de ayuda al diagnóstico basado en inteligencia artificial: ensayo clínico multicéntico aleatorizado con diseño de colonoscopia en tándem. 27ª Reunión Anual de la Asociación Española de Gastroenterología. Madrid, España. 13 - March
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; H. López-Fernández; A. Nogueira-Rodríguez; J.M. Herrero; M. Puga; L. Rivas; E. Sánchez; F. Fdez-Riverola; R. Domínguez-Carbajales; S. Zarraquiños; N. Pin; P. Vega; S. Soto; D. Remedios; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2024) PolyDeep Advance 1: validación clínica de un sistema de ayuda al diagnóstico (CADe/x) basado en inteligencia artificial. 27ª Reunión Anual de la Asociación Española de Gastroenterología. Madrid, España. 13 - March
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; R. Domínguez-Carbajales; J. Herrero; M. Puga; L. Rivas; E. Sánchez; A. Nogueira-Rodríguez; A. González-García; F. Fdez-Riverola; H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2023) Comparison of the diagnostic accuracy of PolyDeep, an artificial intelligence computer-aided diagnosis system (CADE/X) with endoscopists for the characterization of colorectal polyps. 31st United European Gastroenterology Week. Copenhagen, Dinamarca. 14 - October
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; R. Domínguez-Carbajales; J. Herrero; M. Puga; L. Rivas; E. Sánchez; S. Zarraquiños-Martínez; N. Pin; P. Vega; S. Soto; D. Remedios-Espino; A. Nogueira-Rodríguez; A. González-García; F. Fdez-Riverola; H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2023) Clinical validation of polydeep a computer-aided diagnosis system (CADE/X). 31st United European Gastroenterology week. Copenhagen, Dinamarca. 14 - October
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; R. Domínguez-Carbajales; J. Herrero; M. Puga; L. Rivas; E. Sánchez; A. Nogueira-Rodríguez; A. González-García; F. Fdez-Riverola; H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2023) What factors are associated with the optical diagnosis of PolyDeep, a computer-aided diagnosis system (CADE/X)? in vitro analysis. 31st United European Gastroenterology week. Copenhagen, Dinamarca. 14 - October
M.J. Jiménez-Santos; A. Nogueira-Rodríguez; E. Piñeiro-Yáñez; H. López-Fernández; S. García-Martín; P. Gómez-Plana; M. Reboiro-Jato; G. Gómez-López; D. Glez-Peña; F. Al-Shahrour (2023) PanDrugs2: An Integrated Multi-Omics Methodology for Prioritizing Evidence-Based Drugs in Cancer Treatment. VI CINBIO Annual Meeting 2023. Vigo, Spain. 20 - July
H. López-Fernández; M. Pinto; C.P. Vieira; P. Duque; M. Reboiro-Jato; J. Vieira (2023) Auto-phylo: A Pipeline Maker for Phylogenetic Studies. 17th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2023. Guimarães, Portugal. 12 - July
P. Ferreira; R. Soares; H. López-Fernández; C. P. Vieira; J. Vieira (2023) Inferring positively selected amino acid sites (PSS) in Coronavirus species using Auto-PSS-Genome. 3º Encontro Doutoramento em Ciências Biomédicas do ICBAS. Porto, Portugal. 8 - May
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; A. Nogueira-Rodríguez; A. González-García; J.M. Herrero; M. Puga; L. Rivas; E. Sánchez; F. Fdez-Riverola; H. López-Fernández; R. Domínguez-Carbajales; D. Glez-Peña; M. Reboiro-Jato; J. Cubiella (2023) Comparación de la precisión diagnóstica de PolyDeep (sistema de ayuda al diagnóstico basado en inteligencia artificial) frente al endoscopista para la caracterización de pólipos colorrectales. 26ª Reunión Anual de la Asociación Española de Gastroenterología. Madrid, Spain. 29 - March.
P. Davila-Piñón; C. Regueiro; A.I. Díez-Martín; J. Hernández-Camoiras; J.M. Herrero; M. Puga; L. Rivas; E. Sánchez; R. Domínguez-Carbajales; F. Fdez-Riverola; H. López-Fernández; A. Nogueira-Rodríguez; A. González-García; M. Reboiro-Jato; D. Glez-Peña; J. Cubiella (2023) ¿Qué factores se asocian al diagnóstico óptico del sistema de ayuda al diagnóstico, PolyDeep? Análisis in vitro. 26ª Reunión Anual de la Asociación Española de Gastroenterología. Madrid, Spain. 29 - March.
M. Reboiro-Jato; J. Vieira; S. Rocha; A.D. Sousa; H. López-Fernández; C.P. Vieira (2022) EvoPPI 2: an updated version of a powerful Protein-Protein Interaction database aggregator and analysis platform. V CINBIO Annual Meeting 2022. Vigo, Spain. 28 - July
M. Reboiro-Jato; J. Vieira; S. Rocha; A.D. Sousa; H. López-Fernández; C.P. Vieira (2022) EvoPPI 2: a web and local platform for the comparison of protein-protein interaction data from multiple sources from the same and distinct species. 16th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2022. L'Aquila, Italy. 13 - July Presentation file
D. Pérez-Rodríguez; M. Pérez-Rodríguez; R.C. Agís-Balboa; H. López-Fernández (2022) Towards a flexible and portable workflow for analyzing miRNA-seq neuropsychiatric data: an initial replicability assessment. 16th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2022. L'Aquila, Italy. 13 - July
D. Pérez-Rodríguez; H. López-Fernández; R.C. Agís-Balboa (2021) On the reproducibility of miRNA-Seq differential expression analyses in neuropsychiatric diseases. XIII Spanish Drug Discovery Network (SDDN) Meeting. Madrid, Spain. 29 - November
H. López-Fernández; P. Ferreira; M. Reboiro-Jato; C.P. Vieira; J. Vieira (2021) The pegi3s Bioinformatics Docker Images Project. 15th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2021. Salamanca, Spain. 6 - October Presentation file
D. Pérez-Rodríguez; H. López-Fernández; R.C. Agís-Balboa (2021) On the reproducibility of miRNA-Seq differential expression analyses in neuropsychiatric diseases. 15th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2021. Salamanca, Spain. 6 - October
P. Ferreira; H. López-Fernández; C. P. Vieira; J. Vieira (2021) Positively selected sites (PSS) found in Coronaviridae species using Auto-PSS-Genome. II International Meeting of the Portuguese Society of Genetics. Vila Real, Portugal. 1 - July
D. Pérez-Rodríguez; H. López-Fernández; R.C. Agís-Balboa (2021) Re-analysis of miRNA-Seq differential expression analyses in neuropsychiatric diseases. IV CINBIO Annual Meeting 2021. Vigo, Spain. 01 - July
A. Nogueira-Rodríguez; R. Domínguez-Carbajales; F. Campos-Tato; J. Herrero; M. Puga; D. Remedios; L. Rivas; E. Sánchez; Á. Iglesias; L. Codesido; J. Cubiella; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña (2021) Development of a Computer-Aided Diagnosis system based on deep learning for colorectal polyp detection and classification. IV CINBIO Annual Meeting 2021. Vigo, Spain. 01 - July
A. Nogueira-Rodríguez; R. Domínguez-Carbajales; F. Campos-Tato; J. Herrero; M. Puga; D. Remedios; L. Rivas; E. Sánchez; Á. Iglesias; J. Cubiella; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña (2021) Desarrollo de un sistema de Inteligencia Artificial para la detección de pólipos en tiempo real. 24ª Reunión Anual de la Asociación Española de Gastroenterología. 2 - June
A. Nogueira-Rodríguez; R. Domínguez-Carbajales; F. Campos-Tato; J. Herrero; M. Puga; D. Remedios; L. Rivas; E. Sánchez; Á. Iglesias; J. Cubiella; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña (2021) Desarrollo inicial de un Sistema de Diagnóstico Asistido por Computadora (CAD) que facilite el diagnóstico óptico de pólipos colorrectales. 24ª Reunión Anual de la Asociación Española de Gastroenterología. 2 - June
H. López-Fernández; C.P. Vieira; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira (2020) Inferences on Mycobacterium leprae host immune response escape and antibiotic resistance using genomic data and GenomeFastScreen. 14th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2020. L'Aquila, Italy. 7 - October
A. Nogueira-Rodríguez; H. López-Fernández; O. Graña; M. Reboiro-Jato; D. Glez-Peña (2020) Compi Hub: a Public Repository for Sharing and Discovering Compi Pipelines. 14th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2020. L'Aquila, Italy. 7 - October
S. Rocha; J. Vieira; N. Vázquez; H. López-Fernández; F. Fdez-Riverola; M. Reboiro-Jato; A. D. Sousa; C. P. Vieira (2019) Binding differences of wild-type and expanded ATXN1 are mainly explained by the N-terminal region. 8th i3S Annual Meeting. Póvoa de Varzim, Portugal. 28 - November
P. Duque; H. López-Fernández; P. Ferreira; N. Vázquez; F. Fdez-Riverola; M. Reboiro-Jato; C. P. Vieira; J. Vieira (2019) Inferring Positive Selection in Large Viral Datasets. 8th i3S Annual Meeting. Póvoa de Varzim, Portugal. 28 - November
P. Ferreira; H. López-Fernández; P. Duque; C.P. Vieira; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira (2019) Bioinformatics Docker Images. 8th i3S Annual Meeting. Póvoa de Varzim, Portugal. 28 - November
H. López-Fernández; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato (2019) Free and Open-Source Software for Mass Spectrometry Data Analysis. 6th International Congress on Analytical Proteomics: ICAP 2019. Costa de Caparica, Portugal. 8 - July
O. Estévez; L. Anibarro; E. Garet; A. Pallares; L. Barcia; A. Pena; C. Maueia; T. Mussá; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato; H. López-Fernández; N. Fonseca; R. Reljic; A. González (2019) Differential gene expression analysis for the identification of different TB infection profiles. III CINBIO Annual Meeting 2019. Vigo, Spain. 1 - July
P. Ferreira; H. López-Fernández; P. Duque; C.P. Vieira; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira (2019) Bioinformatics Docker Images. III CINBIO Annual Meeting 2019. Vigo, Spain. 1 - July
A. Nogueira-Rodríguez; H. López-Fernández; Á. Iglesias; J.M. Herrero; L. Rivas; M.P. Giménez de Azcarate; E. Sánchez; D. Remedios; F. Fdez-Riverola; J. Cubiella; M. Reboiro-Jato; D. Glez-Peña (2019) Real Time Computer-Aided Diagnosis in Colorectal Cancer using Deep Learning Techniques. III CINBIO Annual Meeting 2019. Vigo, Spain. 1 - July
A. Nogueira-Rodríguez; H. López-Fernández; D. Glez-Peña (2019) Deep Learning Techniques for Real Time Computer-Aided Diagnosis in Colorectal Cancer. 16th International Conference on Distributed Computing and Artificial Intelligence (Special Sessions - Doctoral Consortium): DCAI 2019. Ávila, Spain. 26 - June
H. López-Fernández; P. Duque; N. Vázquez; F. Fdez-Riverola; M. Reboiro-Jato; C.P. Vieira; J. Vieira (2019) Inferring Positive Selection in Large Viral Datasets. 13th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2019. Ávila, Spain. 26 - June Presentation file
O. Graña-Castro; H. López-Fernández; F. Fdez-Riverola; F. Al-Shahrour; D. Glez-Peña (2019) Proposal of a New Bioinformatics Pipeline for Metataxonomics in Precision Medicine. 13th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2019. Ávila, Spain. 26 - June
C.P. Vieira; S. Rocha; N. Vázquez; H. López-Fernández; A. Torres; R. Camacho; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira (2019) EvoPPI 1.0: a Web Platform for Within and Between Species Multiple Interactome Comparisons and Application to Nine polyQ Proteins Determining Neurodegenerative Diseases. Bioinformatics Open Days: BOD 2019. Braga, Portugal. 21 - February
P. Ferreira; H. López-Fernández; P. Duque; Cristina P. Vieira; F. Fdez-Riverola; Miguel Reboiro-Jato; J. Vieira (2019) Bioinformatics Docker Images. Bioinformatics Open Days: BOD 2019. Braga, Portugal. 21 - February
S. Henriques; P. Duque; H. López-Fernández; N. Vázquez; F. Fdez-Riverola; M. Reboiro-Jato; C.P. Vieira; J. Vieira (2018) L-ascorbate synthesis in non-Bilateria and Protostomian species. 7th i3S Annual Meeting. Póvoa de Varzim, Portugal. 29 - November
S. Rocha; N. Vázquez; H. López-Fernández; A. Torres; R. Camacho; F. Fdez-Riverola; M. Reboiro-Jato; J. Vieira; C.P. Vieira (2017) Comparisons of to Nine polyQ Proteins Determining Neurodegenerative Diseases Interactomes, using EvoPPI 1.0- a Web Platform for Within and Between Species comparisons. 7th i3S Annual Meeting. Póvoa de Varzim, Portugal. 29 - November
K. Troulé; M. Reboiro-Jato; H. Tejero; H. López-Fernández; J. Perales-Patón; D. Glez-Peña; F. Al-Shahrour; G. Gómez-López (2018) The druggable immune system: drug repositioning in immune transcriptome. XIV Symposium on Bioinformatics, JBI 2018. Granada, Spain. 14 - November
H. López-Fernández; M. Reboiro-Jato; N. Vázquez; P. Duque; F. Fdez-Riverola; C.P. Vieira; J. Vieira (2018) A toolbox for facilitating the manipulation of FASTA sequences. II CINBIO Annual Meeting 2018. Vigo, Spain. 25 - June
H. López-Fernández; P. Duque; S. Henriques; N. Vázquez; F. Fdez-Riverola; C.P. Vieira; M. Reboiro-Jato; J. Vieira (2018) A bioinformatics protocol for quickly creating large-scale phylogenetic trees. 12th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2018. Toledo, Spain. 20 - June
N. Vázquez; S. Rocha; H. López-Fernández; A. Torres; R. Camacho; F. Fdez-Riverola; J. Vieira; C.P. Vieira; M. Reboiro-Jato (2018) EvoPPI: a web application to compare protein-protein interactions (PPIs) from different databases and species. 12th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2018. Toledo, Spain. 20 - June Presentation file
H. López-Fernández; M. Reboiro-Jato; E. Araújo; H. M. Santos; D. Glez-Peña; F. Fdez-Riverola; J.L. Capelo-Martínez (2018) Facilitating MALDI-TOF mass spectrometry data analysis with S2P and Mass-Up. XII EuPA (European Proteomics Association) Congress. Santiago de Compostela, Spain. 18 - June
J. Vieira; S. Rocha; N. Vázquez; H. López-Fernández; M. Reboiro-Jato; F. Fdez-Riverola; C. P. Vieira (2018) Bioinformatic tools to study Solanaceae S-pollen gametophytic self-incompatibility evolution: BDBM, ADOPS and B+ database. Portuguese Society of Genetics Annual Meeting 2018. Porto, Portugal. 14 - June
S. F. Henriques; P. Duque; H. López-Fernández; C. P. Vieira; J. Vieira (2018) Vitamin C biosynthesis in D. melanogaster: alternatives to GULO and influence of microbiome. Portuguese Society of Genetics Annual Meeting 2018. Porto, Portugal. 14 - June
S. Rocha; J. Vieira; N. Vázquez; H. López-Fernández; S. Macedo-Ribeiro; A. Torres; R. Camacho; F. Fdez-Riverola; M. Reboiro-Jato; C. P. Vieira (2018) New in-silico approach to infer binding surfaces in wild-type and mutant Ataxin-1. Portuguese Society of Genetics Annual Meeting 2018. Porto, Portugal. 14 - June
H. López-Fernández; M. Reboiro-Jato; N. Vázquez; P. Duque; F. Fdez-Riverola; C.P. Vieira; J. Vieira (2018) Developing a standalone toolbox for processing FASTA files. Portuguese Society of Genetics Annual Meeting 2018. Porto, Portugal. 14 - June
H. López-Fernández; M. Reboiro-Jato; N. Vázquez; P. Duque; F. Fdez-Riverola; C.P. Vieira; J. Vieira (2018) Developing a standalone toolbox for processing FASTA files. Bioinformatics Open Days: BOD 2018. Braga, Portugal. 15 - March
H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; R. Laza; R. Pavón; F. Fdez-Riverola (2018) Lessons learned developing GUI in bioinformatics software: from end-user applications to resources for programmers. Bioinformatics Open Days: BOD 2018. Braga, Portugal. 15 - March
C.P. Vieira; N. Vázquez; M. Reboiro-Jato; H. López-Fernández; F. Fdez-Riverola; J. Vieira (2018) Inferring positive selection: ADOPS and B+ database. Bioinformatics Open Days: BOD 2018. Braga, Portugal. 15 - March
I. M. Costa; S. Rocha; H. López-Fernández; I. Guterres de Carvalho; S. Macedo-Ribeiro; R. Camacho; J. Vieira; C.P. Vieira (2018) Comparative evolutionary analyses of the protein-protein interactions of the wild-type polyQ proteins ataxin-2 and androgen receptor, associated with neurodegenerative disorders in Homo sapiens. Encontro de Investigação Jovem da Universidade do Porto: IJUP 2018. Porto, Portugal. 7 - February.
P.M. Baltazar; J.E. Araújo; H. López-Fernández; L. Campos-Pinheiro; F. Calais-Da-Silva; M. Carrascal; P. Videira; H.M. Santos; J.L. Capelo-Martínez (2017) Dithiothreitol-based protein equalization method: A powerful tool in bladder cancer biomarker discovery. 9th European Multidisciplinary Meeting on Urological Cancers. Barcelona, Spain. 16 - November
H. López-Fernández; N. Vázquez; C.P. Vieira; B.S.R. Amorim; A. Torres; F. Fdez-Riverola; José L. R. Sousa; M. Reboiro-Jato; J. Vieira (2017) The B+ repository: a public database of adaptive amino acid changes data. 6th i3S Annual Meeting. Póvoa de Varzim, Portugal. 9 - November
S. Rocha; H. López-Fernández; I. Guterres de Carvalho; I. Costa; S. Macedo-Ribeiro; R. Camacho; J. Vieira; C. P. Vieira (2017) Evolution of the polyglutamine wild-type protein networks, associated to human neurodegenerative diseases. 6th i3S Annual Meeting. Póvoa de Varzim, Portugal. 9 - November
S. F. Henriques; H. López-Fernández; P. Duque; C. P. Vieira; J. Vieira (2017) Evolution of the Vitamin C biosynthetic pathway: role of D. melanogaster Regucalcin and GULO genes in Vit C synthesis and cold acclimatization. 6th i3S Annual Meeting. Póvoa de Varzim, Portugal. 9 - November
F. Teixeira-Costa; J. E. Araújo; H. López-Fernández; S. Jorge; A. Ramos; H. M. Santos; J.L. Capelo-Martínez (2017) Proteomic analysis of the peritoneal dialysis effluent. 3rd International Caparica Conference on Urine OMICS. Caparica, Portugal. 18 - September.
J. Romário de Jesus; H.M. Santos; H. López-Fernández; M.A.Z. Arruda; J.L. Capelo-Martínez (2017) Ultrasonic-Based Membrane Aided Sample Preparation of Urine Proteomes. 3rd International Caparica Conference on Urine OMICS. Caparica, Portugal. 18 - September.
S. Jorge; E. Araújo; H. López-Fernández; H. M. Santos; C. Lodeiro; A. Chiechi; J. Y. Ljubimova; J. L Capelo (2017) The size of the particulate matter addresses the pathways to the brain. Sao Paulo School of Advanced Science on Mass Spectrometry-based Proteomics (SPSAS-MS). Sao Paulo, Brazil. 28 - August.
J. E. Araújo; H. López-Fernández; S. Jorge; F. Teixeira-Costa; A. Ramos; A. Rodrigues; G. Mayer; H. M. Santos; J. L Capelo (2017) Unraveling peritoneal dialysis effluent proteome evolution. Sao Paulo School of Advanced Science on Mass Spectrometry-based Proteomics (SPSAS-MS). Sao Paulo, Brazil. 28 - August.
H. López-Fernández; M. Reboiro-Jato; G. de S. Pessôa; M. A. Z. Arruda; J.E. Araújo; H.M. Santos; F. Fdez-Riverola; D. Glez-Peña; J. L. Capelo-Martínez (2017) Bioinformatics software for effective analysis of mass spectrometry data: S2P, Mass-Up and LA-iMageS. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
H. López-Fernández; J.E. Araújo; H.M. Santos; A. Fernández-Lodeiro; C. Fernández-Lodeiro; J. Djafari; J. Coelho; G. Pinto; N. Morais; G. Marcelo; J. Machado; S. Jorge; J. Prates; E. Oliveira; J. Fernández-Lodeiro; C. Lodeiro-Espiño; J. L. Capelo-Martínez (2017) Using S2P to process emPAI quantitation results obtained from MS/MS Mascot searches. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
J. E. Araújo; S. Jorge; H. M. Santos; C. Lodeiro; J.Y. Ljubimova; H. López-Fernández; J. L. Capelo (2017) Proteomic Dynamic Evolution of Rat Brain Response to Particulate Matter Size. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
S. Jorge; J. E. Araújo; H. López-Fernández; H. M. Santos; C. Lodeiro; Antonella Chiechi; J.Y. Ljubimova; J. L. Capelo (2017) Tracking down the brain-related pathways triggered by particulate matter. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
H. M. Santos; R. Magriço; G. Martins; J. Prates; S. Jorge; E. Araújo; A. Fernández-Lodeiro; J. Djafari; E. Oliveira; J. Fernández-Lodeiro; H. López-Fernández; A. Ramos; C. Lodeiro; J. L. Capelo (2017) Time-resolved proteome profiling of urine and serum of a cysteamine-treated cystinosis patient. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
J. Prates; G. Martins; S. Jorge; E. Araújo; A. Fernández-Lodeiro; J. Djafari; E. Oliveira; J. Fernández-Lodeiro; H. López-Fernández; C. Lodeiro; J. L. Capelo; H. M. Santos (2017) Diagnostics and prognostics utilizing permanent digital maps of non-invasive biopsies of multiple myeloma and lymphoma. V International Conference on Analytical Proteomics. Caparica, Portugal. 3 - July.
H. López-Fernández; J.E. Araújo; D. Glez-Peña; M. Reboiro-Jato; F. Fdez-Riverola; J.L. Capelo-Martínez (2017) S2P: a desktop application for fast and easy processing of 2D-gel and MALDI-based mass spectrometry protein data. 11th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2017. Porto, Portugal. 21 - June Presentation file
N. Vázquez; C.P. Vieira; B.S.R. Amorim; A. Torres; H. López-Fernández; F. Fdez-Riverola; José L. R. Sousa; M. Reboiro-Jato; J. Vieira (2017) Automated collection and sharing of adaptive amino acid changes data. 11th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2017. Porto, Portugal. 21 - June
J.E. Araújo; H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; F. Fdez-Riverola; J.L. Capelo-Martínez (2017) An open-source software for fast and automatic processing of 2D-gel and MALDI-based mass spectrometry protein data. EUBIC Winter School 2017. Semmering, Austria. 10 - January
H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; F. Fdez-Riverola; J.L. Capelo-Martínez; H.M. Santos (2017) Mass-Up and Decision Peptide-Driven: two open-source applications for MALDI-TOF MS data analysis and protein quantification. EUBIC Winter School 2017. Semmering, Austria. 10 - January
H. López-Fernández; M. Reboiro-Jato; G. Pessôa; M.A.Z. Arruda; H.M. Santos; J.L. Capelo-Martínez; F. Fdez-Riverola; D. Glez-Peña (2016) Biomarker discovery and bioimaging bioinformatics tools for mass spectrometry-based applications: Mass-Up and LA-iMageS. II Caparica Christmas Conference on Sample Treatment. Caparica, Portugal. 5 - December.
H. López-Fernández; J. E. Araújo; D. Glez-Peña; M. Reboiro-Jato; F. Fdez-Riverola; J.L. Capelo-Martínez (2016) Fast processing of 2D-gel and MALDI-based mass spectrometry protein data. II Caparica Christmas Conference on Sample Treatment. Caparica, Portugal. 5 - December.
M. Rubio-Camarillo; H. López-Fernández; G. Gómez-López; Á. Carro; J.M. Fernández; F. Fdez-Riverola; D. Glez-Peña; D.G. Pisano (2016) RUbioSeq+: an application that executes parallelized pipelines to analyse next-generation sequencing data. 10th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2016. Sevilla, Spain. 01 - June
H. López-Fernández; J.L. Capelo-Martínez; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato (2014) Understanding data from MALDI-TOF mass spectrometry experiments with Mass-Up. II Jornadas de Investigación Biomédica. Ourense, España. 29 - May
H. López-Fernández; D. Glez-Peña (2014) Bioinformatics Applications in the SING research Group. Case study: Mass‑Up, a proteomics workbench. Bioinformatics Open Days: BOD 2014. Braga, Portugal. 27 - February
T. Santos; J.L. Capelo; H.M. Santos; H. López-Fernández; C. Marinho; P. Poeta; G. Igrejas (2013) Bacterial characterization by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and bioinformatic tools. XXXVIII Jornadas Portuguesas de Genetica. Porto, Portugal. 4 - June
H. López-Fernández; M. Reboiro-Jato; S.C. Madeira; R. López-Cortés; J.D. Nunes-Miranda; H.M. Santos; F. Fdez-Riverola; D. Glez-Peña (2013) A workflow for the application of biclustering to mass spectrometry data. 7th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2013. Salamanca, Spain. 22 - May
H. López-Fernández; D. Glez-Peña; M. Reboiro-Jato; G. Gómez-López; D.G.Pisano; F. Fdez-Riverola (2012) Applying AIBench framework to develop rich user interfaces in NGS studies. 6th International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2012. Salamanca, Spain. 28 - March
R. Carreira; J.D. Nunes-Miranda; H.M. Santos; C. Lodeiro; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; L. Barbeito; J.L. Capelo (2012) Fast sample treatment for bacterial identification. Jornadas de Investigación Biomédica. Ourense, España. 14 - March
H. López-Fernández; F. Aparicio; D. Glez-Peña; M.J. Maña López; M. Buenaga; F. Fdez-Riverola; M. Reboiro-Jato (2012) BioAnote: sistema de anotación de textos médicos mediante ontologías orientado a la formación en medicina. Jornadas de Investigación Biomédica. Ourense, España. 14 - March
M.P. de la Cadena; F. Fdez-Riverola; H. López-Fernández; M. Reboiro-Jato; D. Glez-Peña; J.L. Capelo (2012) Gold-Nanoparticle-Based human plasma profiling helps medical diagnostics. Jornadas de Investigación Biomédica. Ourense, España. 14 - March
H. López-Fernández; F. Aparicio; D. Glez-Peña; M. Buenaga; F. Fdez-Riverola (2011) Herramienta biomédica de anotación y acceso inteligente a información . III Jornada Gallega de Bioinformática. Vigo, España. 16 - September

Books

M. Reboiro-Jato; D. Glez-Peña; H. López-Fernández. Statistics, Data Mining and Modeling. Chapter 5. Pags. 120-200. Processing Metabolomics and Proteomics Data with Open Software, A practical guide. Royal Society of Chemistry. ISBN: 978-1-78801-721-3, PDF eISBN: 978-1-78801-988-0, 2020, England
M. Reboiro-Jato; H. López-Fernández; R. Laza; R. Pavón; F. Rojas Rodríguez; A. Vieira Vázquez; T. Rivera Baltanás; C. Spuch; A. Varela Pomar; F. Otero Lamas; A. Piñón Blanco. MultiTasking Cubes - Unha ferramenta para a rehabilitación cognitiva. Pags. 63-77. Proxectos INOU 2017: Investigación aplicada na provincia de Ourense. Vicerrectoría del Campus de Ourense, Universidad de Vigo. ISBN: 978-84-8158-800-2, 2018, España
H. López-Fernández; G. de S. Pessôa; M. A. Z. Arruda; J. L. Capelo-Martínez; A. Seara Vieira; M. Pérez-Pérez; G. Pérez-Rodríguez; F. Fdez-Riverola; D. Glez-Peña; M. Reboiro-Jato. LA-iMageS: unha ferramenta para a análise e a xeración de bioimaxes mediante ablación láser con fonte de acoplamento indutivo. Pags. 111-128. Proxectos INOU 2016: Investigación aplicada na provincia de Ourense. Vicerectoría del Campus de Ourense, Universidad de Vigo. ISBN: 978-84-8158-760-9, 2017, España
M.R. Pavón; H. López-Fernández; A. Seara; R. Laza. Sistema de clasificación automática de contidos web para o sector do termalismo ourensán. Pags. 107-128. Proxectos INOU 2015: Investigación aplicada na provincia de Ourense. Vicerrectoría del Campus de Ourense, Universidad de Vigo. ISBN: 978-84-8158-717-3, 2016, España
M. Reboiro-Jato; E. Lorenzo Iglesias; J.R. Méndez Reboredo; R. Pavón Rial; H. López-Fernández; F. Fdez-Riverola; D. Glez-Peña, J.L. Capelo; H.M. Santos. Mass-Up: aplicación de software libre para a análise de datos de espectrometría de masas MALDI-TOF. Pags. 101-123. Proxectos INOU 2014: Investigación aplicada na provincia de Ourense. Vicerrectoría del Campus de Ourense, Universidade de Vigo. ISBN: 978-84-8158-698-5, 2015, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Alternativas). Pags. 119-151. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7976-2, 2012, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Servidores). Pags. 153-158. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7976-2, 2012, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Lenguajes). Pags. 1-45. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7978-6, 2012, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Alternativas). Pags. 255-286. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7976-2, 2011, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Servidores). Pags. 287-292. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7976-2, 2011, España
M. Reboiro-Jato; H. López-Fernández. Entorno Tecnológico (Lenguajes). Pags. 1-44. Comercio y Negocio Electrónico. Universidad de Salamanca. ISBN: 978-84-692-7978-6, 2011, España
H. López-Fernández; F. Fdez-Riverola; M. Reboiro-Jato; D. Glez-Peña; J.R. Méndez. Using CBR as design methodology for developing adaptable decision support systems. Pags. 123-144. Efficient Decision Support Systems - Practice and Challenges From Current to Future. Chiang Jao (editor). Intech. ISBN: 978-953-307-326-2, 2011, Croatia

PhD Students

Daniel Pérez Rodríguez (2020 - 2023). Protocolo bioinformático para la búsqueda de miARNs como biomarcadores en enfermedades neuropsiquiátricas.
Defended on 02/10/2023
Summa cum laude
Alba Nogueira Rodríquez (2018 - 2022). Deep learning techniques for computer-aided diagnosis in colorectal cancer.
Defended on 28/07/2022
Summa cum laude

⬇ In progress ⬇

Pedro Davila Piñón (2022 - Present). Validación clínica de un sistema de ayuda al diagnóstico basado en inteligencia artificial para la detección y caracterización de los pólipos colorrectales.
Pedro Miguel da Silva Ferreira (2021 - Present). Predicting the behavior of COVID-19 pandemics.
Rubén Domínguez Carbajales (2018 - Present). Desarrollo de un sistema para la mejora de la calidad de diagnóstico asistido por computador en procedimientos de endoscopia digestiva.

Participation in R&D Projects

Biorrefinarías multiproduto: desenvolvemento de estratexias de proceso para a o aproveitamento e valorización de biomasa lignocelulósica (BioMultiPro) (ED431F 2023/03)

2023 - 2027
Role: Researcher

AI4polypNET: Red Temática enfocada en el Desarrollo y Validación de Sistemas de Soporte al Diagnóstico de Cáncer Colorrectal usando Inteligencia Artificial ( RED2022-134964-T)

01/01/2023 - 31/12/2024
Role: Researcher

PolyDeepAdvance: Validación clínica y plan de acceso al mercado de un sistema CAD basado en Deep Learning para la detección y clasificación de lesiones colorrectales en tiempo real (PDC2021-121644-I00)

01/12/2021 - 30/11/2023
Role: Researcher

Sistemas Informáticos de Nova Xeración (ED431C2018/55-GRC)

01/01/2019 - 31/12/2021
Role: Researcher

PolyDeep: sistema inteligente de detección y clasificación en tiempo real de lesiones colorrectales mediante deep learning (DPI2017-87494-R)

01/01/2018 - 30/06/2021
Role: Researcher (Work team member)

BioData.pt - Infraestructura Portuguesa de Dados Biológicos (LISBOA-01-0145-FEDER-022231)

01/04/2018 - 30/05/2020
Role: Researcher (Work team member)

Centro de Investigaciones Biomédicas (CINBIO) (ED431G/02)

01/01/2016 - 30/11/2019
Role: Researcher

Multitasking Cubes - Unha ferramenta para a rehabilitación cognitiva (INOU17-04)

23/03/2017 - 15/11/2017
Role: Researcher

Ferramenta para a análise e xeración de bioimaxes mediante ablación láser con fonte de acoplamento indutivo (INOU16-05)

11/04/2016 - 15/11/2016
Role: Principal Investigator

Sistema de clasificación automática de contidos web para o sector do termalismo ourensán (INOU15-06)

27/04/2015 - 13/11/2015
Role: Researcher

Biomedical Capacities Support Programe (316265)

01/02/2013 - 31/07/2016
Role: Researcher

Aplicación de técnicas de meta-aprendizaje aplicadas al diagnóstico del cáncer a partir de datos procedentes de microarrays de ADN (INOU10-09)

01/07/2010 - 15/12/2010
Role: Research Trainee (a.k.a. "Becario")

Platform for the development and integration of knowledge-based data mining techniques and their application to the clinical domain (Medical-Bench) (TIN2009-14057-C03-02)

01/01/2010 - 31/12/2012
Role: Research & Technical staff

Participation in R&D Contracts

Plataforma software para a análise científica de datos de saúde e o soporte para a súa implantación do proxecto PI21/01470

22/04/2022 - 22/10/2022
Role: Researcher

Datasets

Polyp Image BAnk database (PIBAdb)

Polyp Image BAnk database (PIBAdb) is a publicly-available dataset of videos and images of colorectal polyps, where each polyp has information about its histological characterization. This dataset was created in the context of the PolyDeep project and includes colonoscopy videos of polyp and not-polyp areas taken under both white light (WL) and narrow band imaging (NBI). In addition, the dataset includes galleries of polyp images annotated with the polyp localizations (as bounding boxes).

Awards

Premios Spin-Off PuntoGal (grupos de investigación) / Grupo SING

10/2022
Asociación PuntoGal, GCiencia

Premios Obxectivo de Desenvolvemento Sostible (ODS) / Grupo SING

07/2022
Colexio Profesional de Enxeñaría en Informática de Galicia (CPEIG)

Premio "Francisco Guitián Ojea" (Premios á Transferencia de Tecnoloxía en Galicia 2022) / PolyDeep

06/2022
Real Academia Galega de Ciencias (RAGC)

Premio "Institución do ano" / InvestiGal

05/2022
Colexio Oficial de Biólogos de Galicia (COBGA)

Dissemination

Post / Combining sklearn’ GridSearchCV with Leave-One-Out Cross-Validation (LOOCV) — Part 2

12/2023

Post / Combining sklearn’ GridSearchCV with Leave-One-Out Cross-Validation (LOOCV)

12/2023

Talk / Impacto da intelixencia artificial nas nosas vidas: pasado, presente e futuro

12/2022
Ciclo Pensando o Futuro organized by Agrupación Cultural Alexandre Bóveda.

Talk / Aplicacións prácticas da Intelixencia Artificial no ámbito sanitario

10/2022
Ciencia con C de CINBIO: Open days for the general public organized by CINBIO.

Infographic / InvestiGal: Que se investiga en Galicia?

05/2022
Montlhy infographics published by InvestiGal to disseminate the scientific activity of their members.

Talk / Aplicacións prácticas da Intelixencia Artificial no ámbito sanitario

11/2021
Ciencia con C de CINBIO: Open days for the general public organized by CINBIO.

Talk / Aplicacións prácticas da Intelixencia Artificial no ámbito sanitario

11/2019
CINBIO conCiencia. Investiga connosco: Open days for the general public organized by CINBIO.

Talk / Aplicacións prácticas da Intelixencia Artificial no ámbito sanitario

11/2018
CINBIO conCiencia. Investiga connosco: Open days for the general public organized by CINBIO.